Dr. Christine Hagan '05; Harvard University, Dept of Chemistry & Chemical Biology, Dan Kahne's Research Group
Seminar Title: "Reconstitution and Inhibition of Integral Membrane Beta-Barrel Assembly."
December 7, 2012 - 3:30 pm to 5:00 pm (already occurred)
b-barrel membrane proteins in Gram-negative bacteria, mitochondria, and chloroplasts are assembled by highly conserved multi-protein complexes. The mechanism by which these molecular machines fold and insert their substrates is poorly understood. It has not been possible to dissect the folding and insertion pathway because the process has not been reproduced in a biochemical system.
Merrill Science Center, Lecture Room 4
Ms. Catherine A. Stillerman (Cathy)