Shirui Chen, Hannah K. Gendelman, John P. Roche, Peter Alsharif, & Ethan R. Graf PLoS One, 28 August 2015, 10:e0136938
Rab3 plays a novel and unexpected role that controls synapse development. How does it do this?
We find that even though the role is new, the general function is conserved. Rab3 likely controls active zone development via a vesicle docking mechanism that is consistent with standard Rab protein function.