Mon, Mar 4, 2019
Board of Trustees Distinguished Professor of Molecular Biology and Biophysics
UConn Health, Farmington, Conn.
Title: "Bacterial Spores: Still Surprises After All These Years"
"Dr. Setlow’s research over the past ~50 years has focused on spore formers of various Bacillus species, concentrating on the mechanisms of the formation, resistance, killing and germination of the spores of these organisms, as well as their biochemical properties, and he has published over 500 research papers on these topics, including definitive studies on the mechanism of spore resistance to 254 nm UV radiation. Dr. Setlow’s research work has utilized techniques from many disciplines, including: 1) microbial physiology; 2) molecular genetics; 3) molecular biology; 4) classical genetics; 5) light, fluorescence and electron microscopy; 6) enzyme purification and characterization; 7) spectroscopy of single cells; 8) small molecule analysis; 9) structural biology; and recently 10) transcriptomics."