Fall 2007

Structural Biology

Listed in: Biology, as BIOL-37


Patrick L. Williamson (Section 01)


This course will concentrate on the structure of proteins at the atomic level. It will include an introduction to methods of structure determination, to databases of structural information, and to publicly available visualization software. These tools will be used to study some class of specific structures, (such as membrane, nucleic acid binding, regulatory, structural, or metabolic proteins). These proteins will provide the framework for discussion of such concepts as domains, motifs, molecular motion, structural homology, etc., as well as addressing how specific biological problems are solved at the atomic level. Four classroom hours per week. Requisites: Biology 19 and Chemistry 12; Chemistry 21 would be helpful but is not required. Limited to 20 students. First semester. Professor Williamson.