The Cell and Molecular Biology of Cancer
Listed in: Biology, as BIOL-34
Richard A. Goldsby (Section 01)
While still mysterious, cancer is now recognized as a set of diseases resulting from molecular aberrations that are traceable to mutations in the genome. Molecular biology and cell biology have emerged as key approaches in the continuing effort to gain a fundamental understanding of the origin, development and pathogenesis of cancer. In this course we will explore the experimental and conceptual foundations of current views of oncogenes, tumor suppressors, multistep carcinogenesis, cancer stem cells, immune responses to cancer and the rational design of targeted chemotherapeutic agents. The work of the course will include lectures and discussions, critical reading of the primary literature of cancer research, and one-on-one tutorials. Three classroom hours per week and regularly scheduled tutorial meetings with the instructor. Requisite: At least one but preferably two or more courses from the following list-- Biology 22, 24, 27, 29, 30, 33, or 37. Limited to 13 students. Open to juniors and seniors or permission from the instructor. Fall semester. Professor Goldsby.