Listed in: Biology, as BIOL-37
Patrick L. Williamson (Section 01)
This course will concentrate on the structure of proteins at the atomic level. It will include an introduction to methods of structure determination, to databases of structural information, and to publicly available visualization software. These tools will be used to study some class of specific structures, (such as membrane, nucleic acid binding, regulatory, structural, or metabolic proteins). These proteins will provide the framework for discussion of such concepts as domains, motifs, molecular motion, structural homology, etc., as well as addressing how specific biological problems are solved at the atomic level. Four classroom hours per week plus one hour discussion .
Requisite: Biology 19 and Chemistry 12; Chemistry 21 would be helpful but is not required. Limited to 20 students. Fall semester. Professor Williamson.
Offerings2013-14: Not offered
Other years: Offered in Fall 2007, Fall 2009, Fall 2010, Fall 2012, Spring 2015
Texts for the course are
Protein Structure and Function, 1st edition, by Gregory A Petsko and Dagmar Ringe (P &R), New Science Press/Sinauer Associates/Blackwell Publishing
Crystallography made Crystal Clear, 3rd edition, by Gale Rhodes, Academic Press
These have been ordered at Amherst Books and are a copy of each is also on reserve in the Merrill Science Library.