Spring 2011

Neurobiology of Disease

Listed in: Biology, as BIOL-36


Stephen A. George (Section 01)


This course explores how translational research applies neuroscience knowledge to prevent, treat, and cure brain diseases.   After reviewing basic neuroanatomy, neuropathology, and neuronal cell biology, we will study Parkinson's, Huntington's, and Alzheimer's diseases, epilepsy, multiple sclerosis, AIDS and equine encephalitis, cerebrovascular disease, trauma, alcoholism and other intoxications, amyotrophic lateral sclerosis, and prion diseases.  Dr. Robert Ferrante of the Boston University School of Medicine, and other neuroscientists doing translational research, will participate in the course.  How are animal models of these diseases developed?  What promises and problems arise in using animal models?   How are pharmacological and other therapeutic strategies derived?  How do we assess genetic influences on human nervous system diseases, and how should we use such knowledge?  Two class meetings per week.

Requisite: Biology 19 and either Neuroscience 26 or Biology 35.  Spring semester.  Professor George.

Cost: 0 ?


2020-21: Not offered
Other years: Offered in Spring 2011, Fall 2012