Fall 2023

Molecular Neurobiology with Lab

Listed in: Biology, as BIOL-301  |  Neuroscience, as NEUR-301


John P. Roche (Sections 01, 01F and 01L)


(Offered as BIOL 301 and NEUR 301) An analysis of the molecules and molecular mechanisms underlying nervous system function, development, and disease. We will explore the proteins that contribute to the unique structure and function of neurons, including an in-depth analysis of synaptic communication and the molecular processes that modify synapses. We will also study the molecular mechanisms that control brain and synapse development as well as neuronal death and degeneration. In addition to analyzing neural function, throughout the course we will also study nervous system dysfunction resulting when such molecular mechanisms fail, leading to neurodevelopmental and neurodegenerative disease. Readings from primary literature will supplement the lectures and also emphasize current molecular techniques utilized in the study of the nervous system. Four classroom hours and three hours of laboratory per week.

While enrolled at the college, students may only take either BIOL/NEUR-301 or BIOL/NEUR-303.

Requisite: Bio 191. Bio/Neur 214 strongly suggested. Limited to 18 students. Fall semester. Professor Roche.

How to handle overenrollment: Priority will first be given to biology and neuroscience seniors who require the course to graduate and then to junior biology and neuroscience majors followed by senior and junior BCBP majors and then by class year or instructor consent.

Students who enroll in this course will likely encounter and be expected to engage in the following intellectual skills, modes of learning, and assessment: Learning in Biol-301 is facilitated by two lectures per week, in addition to group work that is emphasized in both the laboratory and discussion sections. Skills being emphasized is analytical thinking, scientific communication, synthesis, reflection and creativity. Assessments include individual exams, quizzes, lab reports/worksheets, oral presentations and participation laboratory activities.  

BIOL 301 - LEC

Section 01
Tu 10:00 AM - 11:20 AM SCCE E208
Th 10:00 AM - 11:20 AM SCCE E208

BIOL 301 - DIS

Section 01F
Th 11:30 AM - 12:20 PM SCCE A001

BIOL 301 - LAB

Section 01L
W 2:00 PM - 5:00 PM SCCE A001

This is preliminary information about books for this course. Please contact your instructor or the Academic Coordinator for the department, before attempting to purchase these books.

Section(s) ISBN Title Publisher Author(s) Comment Book Store Price
All Principles of Neural Science (5th) McGraw-Hill Professional, 2012 Kandel, et al. Please Order Online/Electronic Copy Available TBD


Other years: Offered in Fall 2011, Fall 2014, Fall 2015, Fall 2016, Spring 2020, Spring 2021, Spring 2022, Fall 2023, Fall 2024