Caroline Goutte

Associate Professor of Biology; Chair of Biology

427 McGuire Life Sciences Building
PO Box: AC# 2237
Phone: 542-8321
E-mail: cegoutte@amherst.edu

Courses in Spring 2008

Departmental Affiliations

Professional and Biographical Informations


Ph.D., University of California, San Francisco, Biochemistry (1992)
B.A., Cornell University, Biology (1985)

Teaching Interests

I am fortunate to be able to teach what I am most passionate about: genetics. In the introductory biology course, Molecules, Genes, and Cells (Biology 19) I aim to bring students a solid picture of the fundamental concepts of molecular and classical genetics, equipping them with enough detail to inspire them to question further and push the limits of their own curiosity and understanding. In Genetic Analysis of Biological Processes (Biology 24) I have the luxury of spending an entire semester dragging students down with me into the trenches of genetic research and the process of scientific discovery. In this course my aim is to teach students how genetic analysis is used to tackle fundamental questions in biology, and I do this by forcing them to become intimately involved in a semester-long genetic quest to understand the yeast mating process. I have also participated in the teaching of Developmental Biology, Seminar in Developmental Genetics, and the first-year seminar Gender and Science.

Selected Publications

Goutte, Caroline, Tsunozaki, Makoto ['00], Hale, Valerie A. and Priess, James R. (2002). APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos. Proceedings of the National Academy of Sciences USA 99:775-779.

Goutte, C. (2002). Genetics leads the way to the accomplices of presenilins. Developmental Cell 3:6-7.

Levitan, Diane, Yu, Gang, Hyslop, Peter St. George, and Goutte, Caroline (2001). APH-2/Nicastrin functions in LIN-12/Notch signaling in the Caenorhabditis elegans somatic gonad. Developmental Biology 240:654-661.

Goutte, Caroline, Hepler, William, Mickey, Katherine M. and Priess, James R. (2000). Aph-2 encodes a novel extracellular protein required for GLP-1 mediated signaling. Development 127:2481-2492.

Awards and Honors

National Science Foundation Award (2002-2006). Program in Developmental Mechanisms, “The Role of APH-1 and APH-2 in Notch-Mediated Cell Interactions in C. elegans"

National Science Foundation Award (1998-2002). Program in Developmental Mechanisms, “New Components of Notch-Mediated Cell-Cell Interactions in C. elegans”

Trustee Faculty Fellowship Award, Amherst College (fall 1999–spring 2000). "A Genetic Search for Molecules that Mediate Cell Communication"

Life Sciences Research Foundation Postdoctoral Fellowship (1992-1995)

Scholarly and Professional Activities

Postdoctoral Fellow, Fred Hutchinson Cancer Research Center, Seattle, WA (1992-1996)

Co-organizer of Teaching Workshops, International C. elegans Meetings, UCLA, CA. (2001-present)

Reviewer for the journals Developmental Biology and Proceedings of the National Academy of Sciences, and for the National Science Foundation's Program in Developmental Mechanism and Program in Evolution of Developmental Mechanisms


See also: Research Interests and Selected Publications