Professor Maren Buck will be visiting from the Smith College Department of Chemistry.
Seminar Title: "Poly(2-alkenyl azlactone)s: Versatile Polymers for the Synthesis of Multifunctional Gels and Drug Delivery Platforms"
"My research interests fall at the intersection of organic chemistry, polymer chemistry and materials science. We use a polymer bearing reactive, azlactone functional groups to assemble multifunctional hydrogels of interest in the contexts of drug delivery, in vitro cell culture, and tissue engineering and regeneration. We are currently developing both complex 2-D and 3-D hydrogel scaffolds functionalized with a broad range of chemical and biological motifs that can direct the behavior of mammalian cells cultured on these materials. A second major area of research focuses on the use of these azlactone-based polymers as macromolecular drug delivery vehicles. We are fabricating nanoscale polymeric micelles that can be used to deliver chemotherapeutics with control over where and when the drug is released. We are also working in collaboration with Sarah Moore’s lab in engineering to synthesize protein-polymer-drug conjugates that specifically target cancer cells as well as cells at the blood-brain barrier."