Professor Ronald T. Raines, Massachusetts Institute of Technology, Department of Chemistry
ABSTRACT: The lipid bilayer that encases human cells has evolved to keep the outside out, and the inside in. This barrier is not, however, impenetrable. Some small molecules, including many drugs, can burrow through and manifest therapeutic activities. Others can be “cloaked” to endow membrane permeability, and then uncloaked inside cells. We have learned how to beneficially cloak proteins, which are typically 100-fold larger than small-molecule drugs. Specifically, the conversion of protein carboxyl groups into esters enables a protein to traverse the lipid bilayer. The nascent esters are substrates for endogenous esterases that regenerate native proteins within cells. The ability to deliver native proteins directly into cells opens a new frontier for molecular medicine.
The foodie media universe offers storytellers with a passion for the culinary the opportunity to share in and define new culinary traditions. Explore the possibilities for your own work—across print, digital, and television—with this behind the scenes look at Crafting a Career in Food Writing. This in-depth discussion will feature three distinguished Amherst community members who will share the details of their trajectories into careers as food writer, cookbook authors, recipe developers and personal chefs.
Lizzy Briskin ’15 is a personal chef, cooking instructor, food writer and recipe developer specializing in healthy, vegetable-forward food.
Dana Cowin P ’22, best known for her two decades as the Editor-in-Chief of Food & Wine, is a tastemaker, talent scout, consultant, author, lecturer and radio show host.
Ted Lee ’93 is co-founder of The Lee Bros. Boiled Peanuts Catalogue, an award winning cookbook author, and host/executive producer of Southern Uncovered with The Lee Bros. on Ovation.
Miki Dezaki, a YouTuber who was threatened and harassed by Japan’s notorious netouyo (cyber neo-nationalists) for his video on racism in Japan, is not shying away from controversial topics with his debut feature-length documentary on the comfort women issue. The film dives deep into the most contentious dispute between Japan and Korea and finds answers to hotly debated questions, such as: Were the comfort women “sexual slaves” or prostitutes? Were they coercively recruited? Were there really 200,000 comfort women? And does Japan have a legal responsibility to apologize?
Dezaki masterfully interweaves footage from demonstrations, man-on-the-street interviews, news and archival clips with in-depth interviews with the most prominent scholars and influencers from both sides of the debate, including Yoshiko Sakurai (journalist), Kent Gilbert (lawyer/celebrity), Mina Watanabe (secretary-general of the Women's Active Museum), Koichi Nakano (political science professor) and Yoshiaki Yoshimi (historian).
Shusenjo includes surprising confessions and revelations that uncover the hidden intentions of both supporters and detractors while deconstructing the dominant narratives. That Dezaki has managed to bring nuance to a sensationalized and often oversimplified issue is just one of the many reasons that Shusenjo: The Main Battleground of the Comfort Women Issue is a must-see work.
Co-sponsored by the Departments of Asian Languages & Civilizations; History; Sexuality, Women’s & Gender Studies; and Film & Media Studies
Join Professor Judith Frank, in conversation with National Book Award recipient Susan Choi and finalist Laila Lalami. This event free an open to the public, to be followed by audience Q&A and book signing. Hosted in partnership with the National Book Foundation.
Susan Choi’s first novel, The Foreign Student, won the Asian American Literary Award for fiction. Her second novel, American Woman, was a finalist for the 2004 Pulitzer Prize and was adapted into a film. Her third novel, A Person of Interest, was a finalist for the 2009 PEN/Faulkner Award. In 2010 she was named the inaugural recipient of the PEN/W.G. Sebald Award. Her fourth novel, My Education, received a 2014 Lambda Literary Award. Her fifth novel, Trust Exercise, and her first book for children, Camp Tiger, came out in 2019. Trust Exercise won the National Book Award for Fiction in 2019. A recipient of fellowships from the National Endowment for the Arts and the Guggenheim Foundation, Choi teaches fiction writing at Yale and lives in Brooklyn.
Laila Lalami was born in Rabat and educated in Morocco, Great Britain and the United States. She is author of the novels Hope and Other Dangerous Pursuits, which was a finalist for the Oregon Book Award; Secret Son, which was on the Orange Prize longlist; and The Moor’s Account, which won the American Book Award, Arab American Book Award and Hurston/Wright Legacy Award, was on the Man Booker Prize longlist and was a finalist for the Pulitzer Prize. Her essays and opinion pieces have appeared in Harper’s, The Guardian, The New York Times and elsewhere. A recipient of British Council, Fulbright and Guggenheim Fellowships, she teaches creative writing at the University of California, Riverside. Her most recent novel, The Other Americans, was a Los Angeles Times best-seller, a best-of-2019 selection from NPR and Time and a finalist for the National Book Award in Fiction.
Judith Frank is author of a book of criticism, Common Ground: Eighteenth-Century English Satiric Fiction and the Poor, and two novels, Crybaby Butch, which won a 2004 Lambda Literary Award, and All I Love and Know. In 2008, Frank received a National Endowment for the Arts fellowship. They have been a resident at Yaddo and the MacDowell Colony and have published short fiction in The Massachusetts Review, Other Voices and Best Lesbian Love Stories 2005. They teach English and creative writing at Amherst College and are currently working on a novel about race, reproduction and queerness.