Deceased October 28, 2022

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In Memory

Paul Anthony “Tony” di Sant’Agnese, M.D., passed away on Oct. 28, 2022, with his devoted wife at his side. 

Tony graduated from Columbia University’s Vagelos College of Physicians and Surgeons in 1975. He was a surgical pathologist and teacher, researcher and department head who practiced at the University of Rochester / Strong Memorial Hospital for 39 years. A giant in the field of prostate research, he was the first author on neuroendocrine differentiation in carcinoma of the prostate (July 1992) and the first person to identify the neuroendocrine prostate cell under a microscope. This discovery of a mutation of common prostate cancer cells allowed for the possibility of prostate cancer cells deviating and displaying different markers, calling for alternative treatment protocols. 

Tony retired in 2014 and moved to Naples, Fla., and Lake Norman, N.C., where he and his wife, Anita, spent many happy years enjoying the beach; swimming in the lake with their golden retriever, Wrigley; and watching fireworks and sunsets from their dock or balcony. 

He was a one-of-a-kind gentle man, a brilliant and curious caretaker of humankind, and an insatiable learner.

Tony is survived by wife Anita, three children and a sister. 

Anita di Sant’Agnese