O
ur group is affiliated with the Department of Chemistry and the Program in Biochemistry & Biophysics at Amherst College. We use the tools and principles of chemistry and biochemistry to study and explore complex biological processes such as cellular signal transduction. For additional information about our current ongoing projects, please view our Research section.
Learn more about the current members of the Bishop lab!
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We use LB/AMP agar plates to culture bacteria, which is carrying a protein production plasmid.
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We use gel electrophoresis to determine the purity of our protein.
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We use 96-well plates to conduct pNPP assays which measure the protein activity.
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This figure is showing the allosteric cysteine of PTP SHP2 which is rare within classical PTP domains. Marsh-Armstrong B,* Fajnzylber JM,* Korntner S,* Plaman BA* & Bishop AC. The allosteric site on SHP2’s protein tyrosine phosphatase domain is targetable with druglike small molecules. ACS Omega 3, 15763-15770 (2018).
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Every summer, the Bishop Lab SURF students engage in research and share their summer research stories and experimental results during the Summer Research Poster Session.
Learn moreAnthony Bishop, Professor of Chemistry at Amherst College and 2010 Dreyfus Teacher-Scholar, gives a talk, “Chemical On/Off Switches for Cellular Enzymes,” at the Dreyfus Teacher-Scholar Conference.
Stem Presidential Teaching Professor of Chemistry; Associate Provost and Associate Dean of the Faculty