Ph. D., Dartmouth College (2008)
M. S., Pohang University of Science and Technology (2002)
B. E., Yonsei University (2000)
Professional Training and Experience
Assistant Scientist, University of Wisconsin-Madison (2014-2015)
Howard Hughes Medical Institute Teaching Fellow, University of Wisconsin-Madison (2013)
Postdoctoral Fellow, University of Wisconsin-Madison (2009-2014)
Molecules, Genes, and Cells (BIOL191)
Molecular Genetics with Laboratory (BIOL/BCBP 371)
Biochemistry with Laboratory (BIOL/BCBP/CHEM 331)
Seminar in Biology of Metals (BIOL 470)
Iron is a metal nutrient essential for nearly all organisms and plays vital roles in fundamental metabolic processes. Paradoxically, the chemical properties that make iron beneficial can cause toxic effects if iron is present in excess or improperly localized. Therefore, iron is tightly regulated at the molecular, cellular, and organismal levels.
My research focuses on understanding the molecular mechanisms that regulate iron in plants. A major global challenge is to sustainably feed the growing population. While caloric malnutrition has significantly decreased, malnutrition of micronutrients, especially iron, affects nearly half of world’s population and is the most deleterious among deficiencies of essential micronutrients. Plants are the primary dietary source of iron worldwide, but plants, especially staple crops, are not rich in iron. To provide a sustainable solution to malnutrition, biofortification, the process of enhancing the nutritional value of crops via selective breeding or genetic engineering, is necessary, and we must understand how iron is regulated in plants to develop strategies for biofortification. Meanwhile, iron is one of the most limiting nutrients for plant growth. Thus, elucidating iron homeostasis in plants is key to improving plant growth, crop yields, and human nutrition.
Amherst College student co-authors are denoted by *.
Park EY'19*, Tsuyuki KM'18*, Hu F'19*, Lee J and Jeong J (2019) PCR2-mediated H3K27me3 contributes to transcriptional regulation of FIT-dependent iron deficiency response. Front. Plant Sci. in press.
Clyne M'17* and Jeong J (2019) How Do Bacteria Fight Back Against Viruses?. Front. Young Minds. 7:2.
Park C '16*, Jeong J. (2018) Synergistic cellular responses to heavy metal exposure: a minireview. Biochim. Biophys. Acta, Gen. Subj. 1862:1584-1591. doi: 10.1016/j.bbagen.2018.04.003
Jeong J, Merkovich A '17*, Clyne M '18*, Connolly EL. (2017) Directing iron transport in dicots: regulation of iron acquisition and translocation. Curr. Opin. Plant Biol. 39:106-113. doi: 10.1016/j.pbi.2017.06.014
MacDiarmid CM, Taggart J, Jeong J, Kerdsomboon K, Eide DJ. (2016) Activation of the yeast UBI4 polyubiquitin gene by Zap1 via an intragenic promoter is critical for zinc-deficient growth. J. Biol. Chem. 291:18880-96.
Jeong J, Eide DJ. (2013) SLC39 family of metal ion transporters. Mol. Asp. Med. 34:612-619.
Jeong J, Walker J, Wang F, Park JG, Palmer AE, Rorhbach M, Giunta C, Steinmann B, Eide DJ. (2012) Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome. Proc. Natl. Acad. Sci.109: E3530-E3538. doi: 10.1073/pnas.1211775110
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Jeong J, Guerinot ML. (2009) Homing in on iron homeostasis in plants. Trends Plant Sci. 14:280-285.
Jeong J, Connolly EL. (2009) Iron uptake mechanisms in plants: functions of the FRO family of ferric reductases: Plant Sci. 176:709-714. doi: 10.1073/pnas.0708367105
Jeong J, Guerinot ML. (2008) Biofortified and bioavailable: The golden standard for plant-based diets. Proc. Natl. Acad. Sci.105:1777-1778. doi: 10.1073/pnas.0712330105
Jeong J, Cohu C, Kerkeb L, Pilon M, Connolly EL, Guerinot ML. (2008) Chloroplast Fe(III) chelate reductase activity is essential for seedling viability under iron limiting conditions. Proc. Natl. Acad. Sci. 152:2301-2308, doi: 10.1073/pnas.0708367105
Jeong J, Suh S, Guan C, Tsay YF, Moran N, Oh CJ, An CS, Demchenko KN, Pawlowski K, Lee Y. (2004) A nodule-specific dicarboxylate transporter from alder is a member of the peptide transporter family. Plant Physiol. 134:969-78. doi: 10.1104/pp.103.032102