Date | Prof | Lab | Topic | Reading |
Introduction; Development of the nervous system | ||||
Jan.24 | JPB/SG | Histology | Introduction to neuroscience | Chapters 1 and 2 |
26 | SG | Neurogenesis, migration | Chapter 7 (178-195); 23 (690-8) | |
28 | Axon pathfinding; cell death | Chapter 23 (698-708) | ||
31 | Electrophysiology I | Role of neural activity in development | ||
| Electrical signaling | |||
Feb. 2 | Membrane potentials | Chapter 3 | ||
4 | Action potential | Chapter 4 | ||
7 | Electrophysiology II | Conductance mechanisms | ||
9 | JPB | Outline of neuroanatomy | Chap. 7 (168-180; 193-199; 205-216; 227-235); Chap. 15 (490-498) | |
|
| Synaptic transmission | ||
11 | SG | Chemical transmission | Chapter 5 (102-122) | |
14 | Neuroanatomy I | Postsynaptic potentials | Chapter 5 (122-131) | |
16 | Neural integration | |||
17/18 |
| Exam 1 | ||
21 | JPB | Neuroanatomy II | Neurotransmitter systems | Chapter 6; Chapter 15 (498-507) |
23 | Quarta D, Valerio E, Hutcheson DM, Hedou G, Heidbreder C. The orexin-1 receptor antagonist SB-334867 reduces amphetamine-evoked dopamine outflow in the shell of the nucleus accumbens and decreases the expression of amphetamine sensitization. Neurocheistry International 56(1) (2010) 11-5. | |||
25 | Pilotte NS, Sharpe LG, Kuhar MJ. Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats. |
Sensorimotor systems | ||||
28 | JPB | Neuroanatomy III | Chemoreception Chapter 8 (252-264) | |
Mar. 2 | Auditory system I | Chapter 11 (344-375) | ||
4 | Auditory system II | |||
7 | Lab Practical | Motor systems: spinal | Chapter 13 | |
9 | Motor systems: brain Chapter 14 | |||
11 | SG | Visual system: retina | Chapter 9 (288-306) | |
Spring break | ||||
21 | SG | Surgery demo | Visual information processing | Chapter 10 (310-329) |
23 | Visual cortex functions Chapter 10 (330-341) | |||
24/25 | Exam 2 | |||
28 | 6OHDA lesions | Visual system plasticity | Chapter 23 (708-716) | |
30 | Somatosensory system | Chapter 12 (388-408) | ||
Apr.1 | Pain Chapter 12 (408-421) | |||
Motivation / Endocrine systems/ Memory | ||||
4 | JPB | Behavior/cfos | Feeding behavior I | Chapter 16 (510-522) |
6 | Feeding behavior II | Chapter 16 (522-531) | ||
8 | Endocrine systems | Chapter 15 (482-490) | ||
11 | HPLC | Stress | Chapter 15 (491-496); 18(573-582); 22 (668-670) | |
13 | ST* | Sexual behavior | Chapter 17 (541-561) | |
15 | SG | Human and animal memory | Chapter 24 | |
18 | Data discussion | Neural plasticity: mechanisms | Chap. 23 (716-722); Chap. 25 | |
20 | Does LTP underlie human and animal memory? | |||
21/22 |
| Exam 3 | ||
25 | JPB | No lab | Brain mechanisms of reward & addiction Chapter 16 (522-27) | |
27 | Reward & addiction II | |||
| Diseases of the nervous system | |||
29 | Depression Chapter 22 (673-678) | |||
May 2 | Angiotensin: thirst | Schizophrenia | Chapter 22 (678-685) | |
4 | SG | Neurodegenerative diseases | ||
6 |
| Alzheimer disease | Box 2.3 p. 36-37 | |
Pick up May 6 - 10 | Final Exam: 3-day take-home |
*Guest lecturer, April 13: Prof. Sarah Turgeon