502 Merrill Science
PO Box: AC# 2243
413-542-2732
Please call the college operator at 413-542-2000 or e-mail info@amherst.edu if you require contact info@amherst.edu

Patricia B. O'Hara

Amanda and Lisa Cross Professor of Chemistry

(On Leave 1/1/2015 - 6/30/2015)

Departmental affiliations: Biochemistry-Biophysics; Chemistry

Interests

Scholarly interests include fluorescence ensemble and single molecule measurements, biomolecular dynamics, and protein - small molecule interactions. My teaching interests are situated in Biophysical and General Chemistry, with some courses in general science topics such as Molecular Gastronomy and Olive Oil Chemistry. At the College, I served on most committees and was Dean of New Students from 2010-2014. In the 2014-2015 academic year, I am on sabbatical, first as a visiting professor at Bo?aziçi University in Istanbul, Turkey and then at Stellenbosch University in Capetown, South Africa.

Curriculum Vitae

EDUCATION
  • Adelphi University, N.Y., B.A., Chemistry, 1976;
  • Columbia University, N.Y., N.Y., 1981, Biophysical Chemistry
POSITIONS
  • 2015- Spring               Visiting Scholar, Stellenbosch University, South Africa
  • 2014-Fall                     Visiting Professor, Boğaziçi University, Istanbul, Turkey
  • 2010-2014                   Dean of New Students
  • 2008-present               Amanda and Lisa Cross Professor of Chemistry
  • 2009 (spring)               Visiting Professor, UMass Amherst Biochemistry w. L. Gierasch
  • 2008-2009                   Senior Advisor to the Dean of Faculty, Amherst College
  • 1995-2008                   Professor of Chemistry, Amherst College, Chair (1999-2002)
  • 2004-2005                   Senior Sabbatical Fellowship, Bordeaux, France
  • 2002-2004                   Talheimer Professorship, Amherst College
  • 1994-1997                   Bruss Reader, Amherst College
  • 1997-1998                   Visiting Professor, UMass Amherst Chemistry w. C. Martin
  • 1993-1994                   Visiting Scientist, Boston Biomedical Research Inst. w. Z. Grabarek
  • 1989-1995                   Associate Professor, Amherst College
  • 1987-1988                   Visiting Professor, Penn. State University w. W.deW.Horrocks
  • 1983-1989                   Assistant Professor, Amherst College
  • 1981-1983                   Postdoctoral Research, Stanford University w. S.G. Boxer
  • 1976-1981                   Graduate Research, Columbia University w. R.A. Bersohn
  • 1974-1976                   Undergraduate Research, Adelphi University w. S.Y. Moon
PUBLICATIONS

Hebda, J., O'Hara, P. (2014) (in reviewJ. Chem. Ed.)Selectivity of Non-Covalent Bonding Interactions Using ELISA as a Mimic for Receptor Function to Differentiate Between the Peptides Vasopressin and Oxytocin in an Undergraduate Lab

 O’Hara, P., Türköz, M., Blatchly, R., Wernz, C., & Delen, Z. (2014) submitted to J. Higher Ed. Outreach and EngagementPlace And Space In Yeni Foça, Turkey: An Interdisciplinary Analysis Of The Olive Culture In A Small Village

 Blatchly, R. A., Delen, Z., O’Hara, P.B.; (2014) J. Chem. Ed. (DOI 10.1021/ed300557r) article, six labsMaking Sense Of Olive Oil: Simple Experiments to Link Sensory Observations with Underlying Chemistry

 Jaswal, S.; O'Hara, P.; Williamson, P.; Springer, A.; (2013)Biochem. & Mol. Bio. Ed. DOI 10.1002/bmb.20718Teaching Structure:  Student Use Of Software Tools For Understanding Macromolecular Structure In An Undergraduate Biochemistry Course

 Pauyo, T.,Hilinski, G. J., Chiu, P.T.,Hansen, D.E.,Choi, Y.C., Ratner, D.I., Shah-Mahoney, N.,Southern,C.A.,O’Hara,P.B. (2006) Mol. Imm. Vol 43/7 pp 812-821Genetic and Physical Studies of Affinity Maturation in Related Antibodies.

 O’Hara, P.B., Engelson, C., and St. Peter, W. (2005)J. Chem. Ed. 82 1 (includes manuscript, five labs) Turning on the Light: Lessons from Luminescence Also

 O'Hara, P.B., Engelson, C. St. Peter, W., (2005) J. Chem. Educ. Activity:  82, p48A Turning on the Light

 Mohan, G. S., Chiu, P.T., Southern, C.A.,O’Hara, P.B., (2004) J.Phys.Chem. A 108, 7871-7877Steady State and Multifrequency Phase Fluorometry Studies of Binding Site Flexibility in Related Antibodies

 O’Hara, P.B., Howard, M.L.1., Sanborn, J.A., (1999) J. Chem. Educ.76 p1673-1677.GC/MS and Immunoassays of Pesticides in Drinking Water: A Project Based Approach to Introductory Chemistry

 O’Hara, P. B.  (1997) Calcium Binding Proteins, Celio editor, Oxford University Press 1996 J. Amer. Chem. Soc, 119, p8581.

 O’Hara, P.B., Rahman, M.A., Rowland, A., and Turjoman, A.J., (1995) Photochem. and Photobio. B Biology 30 p15-21.Target Peptide Induced Changes in the Structure and Dynamics of Calmodulin as Probed by Frequency Domain Fluorometry of Bound Tb(III)

 O’Hara, P.B., Gorski, K.M., Rosen, M. (1988) Biophys. J. 53, 1007-1014Thermal Profiles of Energy Transfer: Luminescent Probes of Protein Dynamics in Transferrin and Calmodulin

 O’Hara, P.B., Gorski, K.M. (1988) Anal. Chim. Acta. 205, 161.Luminescent Probes of Protein Dynamics: Preliminary Results of Thermal Profiles of Förster Energy Transfer in Proteins

 O’Hara, P.B. (1987) Photochem. Photobio. 46 1067.nvited Paper Lanthanide Ions as Luminescent Probes of Biomolecular Structure

 O’Hara, P.B. and Koenig, S. (1986) Biochemistry 25, 1445.ESR and Magnetic Relax. Studies of Gd(III) Complexes with Human Serum Transferrin

 O’Hara, P.B. (1985) J. Amer. Chem Soc. 107, 4365. (H. Siegel, ed)Review of Calcium and its Role in Biology Metal Ions in Biological Chem 17

 O’Hara, P.B. and Bersohn, R. (1982) Biochemistry 21, 5269.Resolution of the Two Metal Binding Sites of Human Serum Transferrin by Low Temperature Excitation of Bound Eu(III)

 Sommer, J.H., O'Hara, P.B., Jonah, C., Bersohn, R. (1982) Biochem. Biophys. Acta 703, 62.Relative Reducibilities of Complexes of Fe(III), Co(III), Mn(III), and Cu(II) with Apotransferrin Using Solvated Electrons and CO2-

 O'Hara, P.B., Yeh, S.M., Meares, C.F., and Bersohn, R. (1981) Biochemistry 20, 4704.The Intersite Distance in Transferrin Measured by Energy Transfer From Tb+3 to Mn+3 or Fe+3

 O'Hara, P.B. (1981) PhD Thesis, Columbia University, N.Y., N.Y.The Binding Sites of Transferrin: Spectroscopic and Magnetic Studies of Lanthanide and Transition Metal Complexes

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