Neuroscience Senior Comprehensives Schedule and Readings

All the articles (full version) are available in the file "Article pdfs" under Comprehensive Schedule in the left hand column.  You must log in to see the articles.

The written exam will take place on Sunday January 25th from 7-9 pm.  The exam will consist of questions based on the following two papers.   Clean copies of the papers will be provided at the exam. Professors will not answer questions about the papers prior to the exam.  The first two papers listed below are for the written exam.

Endogenous opioid-induced neuroplasticity of dopaminergic neurons in the ventral tegmental area influences natural and opiate reward.  Pitchers KK, Coppens CM, Beloate LN, Fuller J, Van S, Frohmader KS, Laviolette SR, Lehman MN, & Coolen LM.  The Journal of Neuroscience, 2014, Jun 25;34(26):8825-36. doi: 10.1523/J,  0133-14.2014.

Regulation of Hippocampal Synaptic Strength by Glial xCT.  Williams, L.E., & Featherstone, D.E. The Journal of Neuroscience,26 November 2014,34(48):16093-16102.


 If you prefer to give an oral exam, you should choose one article from the following list.  Oral presentations will be on either Thursday, January 29, or Thursday, February 5, 2015.  Please email Professor Turgeon with your first and second article choices and preferred date.  You must submit your preference by January 12th, 2015.

LTP and LTD in the Visual Cortex Require the Activation of NOX2 .De Pasquale, R. Beckhauser, T.F., Sorrentino Hernandes, M., & Giorgetti Britto, L.R. The Journal of Neuroscience,17 September 2014, 34(38):12778-12787.

MET Receptor Tyrosine Kinase Controls Dendritic Complexity, Spine Morphogenesis, and Glutamatergic Synapse Maturation in the Hippocampus.  Qiu, S., Zhongming, L., & Levitt, P.  The Journal of Neuroscience,3 December 2014, 34(49):16166-16179

The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons.  Baiping, W., Wang, Z., Sun, L., Yang, L. et al.  The Journal of Neuroscience,1 October 2014, 34(40):13314-13325..

Long-Term Seizure Suppression and Optogenetic Analyses of Synaptic Connectivity in Epileptic Mice with Hippocampal Grafts of GABAergic Interneurons. Henderson, K. Gupta, J., Tagliatela, S., et al. The Journal of Neuroscience,1 October 2014, 34(40):13492-13504.

LRP4 Is Critical for Neuromuscular Junction Maintenance. Barik, A., Lu, Y., Sathyamurthy, A. et al. The Journal of Neuroscience,15 October 2014, 34(42):13892-13905

KIS, a Kinase Associated with Microtubule Regulators, Enhances Translation of AMPA Receptors and Stimulates Dendritic Spine Remodeling. Pedraza, N., Ortiz, R.,. Cornado, A., Llobet, A., Aldea, M., & Gallego, C. The Journal of Neuroscience,15 October 2014, 34(42):13988. 13997.

Cannabinoid transmission in the prefrontal cortex bi-phasically controls emotional memory formation via functional interactions with the ventral tegmental area.  Draycott B, Loureiro M, Ahmad T, Tan H, Zunder J, Laviolette SR.  The Journal of Neuroscience, 2014 Sep 24;34(39):13096-109. doi: 10.1523/JNEUROSCI.1297-14.2014.

Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats.   Melis M, Sagheddu C, De Felice M, Casti A, Madeddu C, Spiga S, Muntoni AL, Mackie K, Marsicano G, Colombo G, Castelli MP, Pistis M The Journal of Neuroscience. 2014 Sep 17;34(38):12716-24. doi: 10.1523/JNEUROSCI.1844-14.2014.


A new pathway mediating social effects on the endocrine system: female presence acting via norepinephrine release stimulates gonadotropin-inhibitory hormone in the paraventricular nucleus and suppresses luteinizing hormone in quail.  Tobari Y, Son YL, Ubuka T, Hasegawa Y, Tsutsui K.    The Journal of Neuroscience, 2014 Jul 16;34(29):9803-11. doi: 10.1523/JNEUROSCI.3706-13.2014.


Neural structures mediating expression and extinction of platform-mediated avoidance. Bravo-Rivera C, Roman-Ortiz C, Brignoni-Perez E, Sotres-Bayon F, Quirk GJ.J  The Journal of Neuroscience 2014 Jul 16;34(29):9736-42. doi: 10.1523/JNEUROSCI.0191-14.2014.


Too little and too much: hypoactivation and disinhibition of medial prefrontal cortex cause attentional deficits.  Pezze M, McGarrity S, Mason R, Fone KC, Bast T.  The Journal of Neuroscience,   2014 Jun 4;34(23):7931-46. doi: 10.1523/JNEUROSCI.3450-13.2014.


Hyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning.  Thiebaud N, Johnson MC, Butler JL, Bell GA, Ferguson KL, Fadool AR, Fadool JC, Gale AM, Gale DS, Fadool DA.  The Journal of Neuroscience, 2014 May 14;34(20):6970-84. doi: 10.1523/JNEUROSCI.3366-13.2014.

Genetic identification of a neural circuit that suppresses appetite. Carter ME, Soden ME, Zweifel LS, Palmiter RD. Nature, 2013 Nov 7;503(7474):111-4. doi: 10.1038/nature12596. Epub 2013 Oct 13.

Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus→midbrain pathway for feeding behavior.  Stachniak, TJ., Ghosh, A., & Sternson, S.M. Neuron, 2014 May 21;82(4):797-808. doi: 10.1016/j.neuron.2014.04.008. Epub 2014 Apr 24.

The Molecular and Cellular Basis of Taste Coding in the Legs of Drosophila.   Ling, F., Dahanukar, A.,  Weiss, L.A., Young Kwon, J. & Carlson, J.  The Journal of Neuroscience, 2014, May 21; 34(21):7148-7164.

Nucleus Accumbens Dopamine/Glutamate Interaction Switches Modes to Generate Desire versus Dread: D1 Alone for Appetitive Eating But D1 and D2 Together for Fear.  Richard, J.M., & Berridge, K.C. The Journal of Neuroscience, 7 September 2011, 31(36): 12866-12879; doi: 10.1523/JNEUROSCI.1339-11.2011.

Dynamic Computation of Incentive Salience: “Wanting” What Was Never “Liked.”  Tindell, A.J., Smith, K.S., Berridge, K.C., & Aldridge, J.W.  The Journal of Neuroscience,30 September 2009, 29(39): 12220-12228; doi: 10.1523/JNEUROSCI.2499-09.2009.

Manipulating a “Cocaine Engram” in Mice.  H.L. Hsiang, Epp, J.R., van den Oever, M.C. et alThe Journal of Neuroscience,15 October 2014, 34(42):14115-14127.